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The amino acid sequence is in the public domain and there is no composition-of-matter patent worth pursuing, so no commercial sponsor will fund the hundreds of millions a Phase IIIII development programme costs for a compound it cannot exclusively monetise

2010 Sep;28(9):1155-61

The same applies to oral vitamin C bioavailability is roughly 3050% from oral doses, compared with near-100% intravenously, and blood concentrations achievable via IV simply cannot be reached orally

Ive heard some chatter about autoimmunity

Shanhua, Tainan: World Vegetable Center

Gynostemma: pianta adattogena in grado di aumentare la resistenza dellorganismo allo stress