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Sanmiguel CP, Hagiike M, Mintchev MP, et al

Peripheral neuropathy is nerve damage caused by a variety of conditions, such as trauma, infections, metabolic issues, Diabetes, genetic reasons, and exposure to toxins

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Animal studies have generally reported good tolerability at the doses tested, and peptides as a class tend to have high target specificity

Goldberg PL, MacNaughton DE, Clements RT et al

SIN has therapeutic effects in streptozotocin-induced gestational diabetes mellitus (GDM) rats with high safety, which is associated with the inhibition of inflammation and oxidative stress via the TLR4/MyD88/NF-B signaling pathway (130)