As a protease, HDAC2 plays an important role in the modification of chromosome structure and regulation of gene expression and is related to the deacetylation of a variety of transcription factors, receptors and histones
Their regulatory approval for obesity (liraglutide in 2014 and semaglutide in 20212022) may also contribute to the predominance of older individuals among treated people [3, 18, 19]
Calculation of IC 025 for these drugs is consistent with the procedure described in section 2.5
Adherence in real-world settings is often limited by side effects, cost, and perceived lack of benefit, complicating translation from trials to clinical practice (Table 2)
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TMG is often paired with B vitamins, especially folate, B6, and B12, to enhance its ability to regulate homocysteine levels effectively