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In some individuals, this drop may lead to the return of hunger signals, changes in satiety, or fluctuations in metabolic markers

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Every escalation decision is reviewed by an independent Safety Review Committee, which evaluates all available data against predefined stopping rules

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10.3389/fphys.2020.575722 55 JiaoB.AnC.TranM.DuH.WangP.ZhouD.et al (2021a)

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