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The 2023 International PCOS Guideline remains cautious about the role of GLP-1RAs: their core indications remain limited to weight management and metabolic risk control

When targeted correctly, they can tell the body to: Stimulate collagen and elastin synthesis Accelerate wound healing and tissue remodeling Improve skin barrier integrity Promote angiogenesis (new blood vessel formation), enhancing nutrient delivery to skin and hair follicles Reactivate dormant hair follicles and improve hair shaft thickness Most cosmetic products containing peptides only affect the outermost layers of skin