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Rather than triggering GLP-1 and GIP production in the body, the supplement mimics these hormones but is not broken down so quickly by the enzyme DPP-4, which starts breaking down naturally-produced GLP-1 within minutes

This remains an area of ongoing investigation in longer-term studies [3]

This leads to a reduction in TCA cycle gene expression and oxygen consumption as well as an increase in lactate production and cell proliferation 89

Report any suspected side effects from Rybelsus via the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk or via the Yellow Card app)

Atrial fibrillation/flutter As with other beta blockers, metoprolol tartrate can help slow down your heart rate