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Conclusion GLP-1 agonist therapy, while clinically valuable, can result in significant facial ageing due to fat loss
CCK concentrations increase from fivefold to tenfold after ingestion of a mixed meal and inhibit gastric emptying through activation of CCK-1 receptors (104)
10.1016/j.metabol.2024.156043 47 LoombaR.AbdelmalekM
T his makes them a valuable option for patients with both diabetes and cardiovascular concerns
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TRIUMPH-4: Efficacy at 68 weeks TRIUMPH-4 (ClinicalTrials.gov identifier NCT05931367) enrolled 445 adults with obesity or overweight plus symptomatic knee osteoarthritis and no type 2 diabetes
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