ES911020: 4-Nitrophenyl 6-O-α-D-Glucopyranosyl-α-D-Glucopyranoside Pack Size:25 mg producing high-avidity binding that substantially

producing high-avidity binding that substantially exceeds the affinity of monovalent GalNAc ligands and closely mimics the geometry of clinically validated Tri-GalNAc targeting moieties used in approved GalNAc-siRNA therapeutics

The terminal amine is protected with a benzyloxycarbonyl (Cbz) group

/ Fmoc-Ser(GlcNAcβ(1-3)GalNAc)-OH (Peracetate) / Core 3 O-Glycan on Serine

N-α-Fmoc-O-β-(2-acetamido-3

This compound provides a β-N-acetylglucosamine (GlcNAcβ) building block for glycoconjugate synthesis and the construction of probes for GlcNAc-recognizing proteins

ES911020: 4-Nitrophenyl 6-O-α-D-Glucopyranosyl-α-D-Glucopyranoside Pack Size:25 mg producing high-avidity binding that substantiallyC18H25NO13 463. 39 A 4 nitrophenyl glycoside of isomaltose (Glc1 6Glc), an 1 6 linked glucose disaccharide. Used as a chromogenic substrate for glucosidases and isomaltases with 1 6 linkage selectivity (e. g., sucrase isomaltase, oligo 1,6 glucosidase, and other debranching glucosidases); enzymatic cleavage of the aglycone proximal glucosidic bond releases 4 nitrophenol. 4 Nitrophenyl (pNP) glycosides are chromogenic enzyme substrates: cleavage of the