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The Panel notes that if a clinician chooses to administer a "cocktail" preparation, then he or she should be aware that DMSO potentially enhances absorption of other substances, creating the possibility for toxicity from drugs such as lidocaine

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Circulating iron, in the form of ferric iron (Fe 3+ ) bound to transferrin, is transported into cells through the membrane-bound transferrin receptor 1 (TfR1)

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