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Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
For long-term studies, this can sometimes present practical challenges, especially if high frequency of administration is required
Azagra-Boronat I, Massot-Cladera M, Knipping K, Garssen J, Ben Amor K, Knol J, et al
Key points: GLP-1 use: More patients are presenting for procedures while taking GLP-1RAs for diabetes or weight loss Main concern: GLP-1RAs can delay gastric emptying, which may increase aspiration risk during sedation Continue therapy: Current guidance supports continuing GLP-1RAs in patients without significant aspiration risk, using shared decision-making Assess risk factors: Recent start or dose escalation, weekly/high-dose therapy, GI symptoms, gastroparesis or other motility disorders Key takeaway: Most interventional pain procedures can be performed safely with local anesthetic alone, making conscious sedation unnecessary in many cases Conclusion: This study highlights the importance of individualized risk assessment and avoiding unnecessary sedation to improve safety in patients taking GLP-1RAs
