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Of note, development of these cells required the presence of an intact microbiota and the activity of CD11c(+) dendritic cells, along with innate immune factors operating through Toll-like receptor-2

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In research studies, it is commonly investigated for its potential roles in promoting tissue repair, reducing inflammation, and supporting gastrointestinal health

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The relative gene expression was calculated using the 2 CT method by Ribosomal protein L13a ( RPL13 ) gene, and the fold change was expressed by 2 CT