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Another class of medications initially developed for the treatment of high blood glucose in patients with type 2 diabetes, sodium-glucose cotransporter 2 inhibitors (SGLT2i), has also been demonstrated to reduce cardiovascular risk, with corresponding FDA product label changes and professional society recommendations endorsing their use

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For type 2 diabetes indications, Tennessee Medicaid (TennCare) requires documented A1C above 7.0% despite maximum-dose metformin therapy for at least 90 days, plus a signed attestation from the prescribing physician that the patient has no contraindications to GLP-1 therapy

doi:10.1089/ARS.2009.2695