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GLP-1RAs pose risks of severe eye complications, particularly worsening diabetic retinopathy with rapid and significant HbA1c reduction

Source: The potential of GHK as an anti-aging peptide (2020) Claim 2: Intranasal administration bypasses the blood-brain barrier (BBB) to enhance central nervous system (CNS) delivery

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GLP-2-mediated increases in IGF-1 activates the IGF-1 receptor on intestinal epithelial cells to stimulate proliferation (Rowland et al., 2011)