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Here, we present a 19-year-old female who was diagnosed with glutathione synthetase deficiency shortly after birth and who has been closely followed in our metabolic clinic

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Varecha, M., J

Indeed, the parameters used, such as biomarkers of mitochondrial function, plasma levels of inflammatory markers, or ischemiareperfusion lesions in organs, do not directly reflect the ability of these compounds to improve survival

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The addition of glucagon receptor agonism introduces theoretical concerns about hepatic glucose output, though no clinically significant hyperglycemia was observed