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As weight-loss medications like Ozempic and Wegovy continue to make headlines and surge in popularity, some people are experimenting with a trend called GLP-1 microdosing the off-label use of GLP-1 medications at a fraction of the FDA-recommended dose

Deciding between weight loss injections and tablets comes down to cost, convenience, and how much weight you need to lose

These effects were substantial and help elucidate the remarkable glucose homeostasis abilities of tirzepatide observed in SURPASS-2 trial when compared with semaglutide (112)

However, most of the doses in the studies mentioned in the review are far higher than those likely (or possibly) in Grns

Ard, J., Fitch, A., Fruh, S

Medicare is now covering some GLP-1 weight loss drugs for $50