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However, in older adults with co-morbidities or those with sarcopenic obesity, even modest reductions in lean mass can exacerbate functional decline [24]

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It is crucial to weigh the potential advantages against the risks, especially for patients with a predisposition to colorectal cancer. Ongoing research aims to clarify the relationship between GLP-1 receptor agonists and colorectal cancer

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Investment analysts expect production costs of orforglipron to be 30 to 50% lower than injectables