Microdosing GLP-1 Receptor Agonists During Perimenopause: A Clinical Approach to Hormonal Weight Gain Written and edited by Sarah Bonza MD, MPH, FAAFP, MSCP, DipABLM, NBC-HWC Perimenopause represents a challenging time for women, with up to 70% experiencing weight gain due to declining estrogen levels, decreased energy expenditure, and metabolic changes
The efficacy estimand represents efficacy had all randomized participants remained on study intervention (with possible dose interruptions and modifications) without initiating prohibited weight management treatments
It is also important to mention, that the Beta-Carotene and Retinol Efficacy Trial (CARET) tested daily intake of the combination of 30 mg beta-carotene and 25,000 IU vitamin A against placebo in 18,314 men and women
Glycine, an amino acid, may support muscle protein synthesis when combined with adequate protein intake and resistance training
1,2,3 These prescription drugs serve to release the hormone (GLP-1) that in turn releases insulin, which helps balance metabolic processes as well as glucose
doi: 10.1001/jama.2019.2942 56 PratleyRAmodAHoffSTKadowakiTLingvayINauckMet al
