Discussion In this study, we used a de-identified patient EHR database to analyze the real-world response of T2D patients to GLP-1 M treatment and to predict which patients might benefit most from this class of T2D medications
GLP-1 mediations like semaglutide (Ozempic, Wegovy, Rybelsus) and tirzepatide (Mounjaro, Zepbound) are FDA-approved prescription medications that have shown powerful results for people with obesity and type 2 diabetes
It is worth mentioning that endurance training performed over a period of 4 weeks or longer caused an adaptive increase in amylase activity in rats, which was associated with an increased ability to digest carbohydrates and, as a result, with a greater accumulation of glycogen in the muscles, which leads to an increased exercise capacity 31,32,64
Wider Access to GLP1 Therapies & Tirzepatide GLP1 receptor agonists and tirzepatide will be recommended earlier for those with: Heart disease Obesity Early-onset diabetes (e.g., before age 40) These drugs also help reduce cardiovascular and kidney risks
Research shows it can cause spontaneous erections in some studies, suggesting biological activity
doi: 10.1016/j.ijid.2021.09.043 106 OaklanderALMillsAJKelleyMToranLSSmithBDalakasMCet al
