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Despite the early termination of the trial, it is interesting to note that 13 of 140 patients had a median duration of response of 10.2 months, indicating that these patients benefited from combination therapy and that exploring the mechanisms of this benefit should be the focus of future research

[19] [21] If a dose is missed, it should be administered as soon as possible, unless it is almost time for the next scheduled dose

Bioinformatics 30 , 923930 (2014)

While TNF- and IL-6 are well-detailed promoters of endometriotic proliferation and correlate disease severity, the role of IFN- signaling remains unclear 14,15

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The measurement of total serum selenium concentration or circulating selenoproteins, including GPX-3 and selenoprotein P, can be used to evaluate the selenium status, which is variable depending on the geographical area, being high in North America and relatively low in most European countries, in particular in the Eastern Europe (5052)