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Protection against stroke with glucagon-like peptide-1 receptor agonists: A comprehensive review of potential mechanisms

This value is adequately adjusted with the CRP reductions associated with the use of semaglutide observed in some of the studies included in this review (range between 39.1% and 59.6%) ( Evidence from epidemiological studies has shown that elevated CRP levels, a surrogate for systemic inflammation, are associated with increased cardiovascular risk ( In clinical practice, CRP values exceeding 3 mg/L are considered as a marker of cardiovascular risk ( Several drugs evaluated in the field of cardiovascular prevention have shown to simultaneously have an anti-inflammatory (CRP lowering) and cardioprotective effect (decrease in cardiovascular atherosclerotic events)

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