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A40 is comparatively benign and may even be protective (reviewed in Karran et al., 2011

It is commonly used in hormone replacement therapy (HRT) to support growth hormone levels, which naturally decline with age

[DOI: 10.1371/journal.pmed.1000100] [DOI] [PMC free article] [PubMed] [Google Scholar] Lindenbaum 1994 Lindenbaum J, Rosenberg IH, Wilson PW, Stabler SP, Allen RH

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According to the National Institutes of Health, Vitamin B12 or cobalamin is a water-soluble vitamin that plays an important role in red blood cell formation, cell metabolism, nerve function and the production of DNA