MS250000: 4-Fluoro-N-Acetylglucosamine Pack Size:5 mg providing a straightforward route to

providing a straightforward route to conjugate the glycan onto NHS-activated molecules and surfaces

tri-GalNAc COOH

β-D-GalNAc-Hexyl-NH-Cbz

The maleimide reacts selectively with free thiols

5-Dihydro-5-oxo-1

MS250000: 4-Fluoro-N-Acetylglucosamine Pack Size:5 mg providing a straightforward route toC8H14FNO5 223. 2 A fluorinated N acetylglucosamine analog in which the C4 hydroxyl is replaced by a fluorine. Fluorinated GlcNAc analogs are valuable probes for studying GlcNAc processing enzymes (O GlcNAc transferase OGA, hexosaminidases, glycosyltransferases) and as metabolic inhibitors of N glycan, O GlcNAc, and glycosaminoglycan biosynthesis. The carbon fluorine bond is stable, isosteric with the native hydroxyl, and provides a handle for F NMR