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doi: 10.3389/fcvm.2025.1574489 Received 10 February 2025 Accepted 03 March 2025 Published 25 March 2025 Volume 12 - 2025 Edited by Ryuichi Morishita, Osaka University, Japan Reviewed by Chieko Mineo, University of Texas Southwestern Medical Center, United States Kimie Tanaka, Juntendo University, Japan Updates Copyright 2025 Jha, Nakano, Itto, Barbeiro, Lupieri, Aikawa and Aikawa

Pinzani M, Abboud HE, Aron DC: Secretion of insulin-like growth factor-I and binding proteins by rat liver fat-storing cells: regulatory role of platelet-derived growth factor

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Clinical trials represent the most resource-intensive and failure-prone phase of drug R&Dand are even more complex in the context of rare diseases (Table 1)