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This matters because heart disease remains the leading cause of death worldwide, and excess weight strongly increases cardiovascular risk

Calculator pages are educational tools for laboratory planning and should be cross-checked against professional protocols, institutional requirements, and applicable laws

To prevent acidification of the cell, pyruvate is also transaminated into alanine and lactate is transported out of the cell thereby acidifying the extracellular environment

Lancet 368(9548):16961705 Muskiet MHA, Tonneijck L, Smits MM, Van Baar MJB, Kramer MHH, Hoorn EJ et al (2017) GLP-1 and the kidney: From physiology to pharmacology and outcomes in diabetes

Previous trials in HFpEF enrolled many thousands of patients

They're appearing consistently enough that researchers are beginning to pay attention