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Sources Efficacy and safety of semaglutide 2.4 mg for weight loss in overweight or obese adults without diabetes: An updated systematic review and meta-analysis including the 2-year STEP 5 trial

each component must serve its purpose exactly, no more and no less

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GLP-1 agonists and dual GLP-1/GIP agonists are the newest ones, but older drug classes like lipase inhibitors, phentermine, and combination medications may be appropriate in certain circumstances