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integration time: 40 s

Most information comes from animal models and involves GH signaling in the liver, but in mouse adipose tissue GHR KO downregulates beta-3 adrenergic receptor expression and inhibits lipolysis (73)

These protective responses have been associated with coordinated biological actions involving vascular support, regenerative signaling, and regulation of inflammatory activity, collectively contributing to enhanced tissue resilience and recovery in injury models

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(2008) method 58