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2021;35:e21620

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It was found that exercise increased NAD + levels, enhancing mitochondrial complex activities in the brain and resulting in improved motor performance 307

Ultrastructure analysis shows that when ferroptosis occurs,cell membrane rupture and bubbles occur, mitochondria decrease, mitochondria atrophy, the mitochondrial spine decreases or even disappears, and mitochondrial membrane density increases, possibly due to dysfunction of varistor anion channels (VDACs) and alterations in the fluidity of mitochondrial membranes [45]