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Administration technique proves critical - head tilted slightly forward not back to prevent throat drainage, alternating nostrils with 1-2 minute intervals, avoiding immediate deep sniffing, and allowing adequate mucosal contact time

Cosmo Fowler, a sleep medicine physician at Piedmont health system in Atlanta, said in a news release

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Am J Clin Nutr 90(5):12361243 Celestino MM, Gomes AC, Botelho PB, Gambero A, Mesquita LM, Vilegas W, Ribeiro ML, Mota JF (2017) South American herbal extracts reduce food intake through modulation of gastrointestinal hormones in overweight and obese women

Many GLP-1 users do best with 4-5 smaller, more frequent meals rather than 3 large ones