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Stomach acid can break down the active ingredients, and not all of the nutrients will be absorbed into your bloodstream

(PubMed) Polymeropoulos E, Bagos P, Papadimitriou M, Rizos I, Patsouris E, Tauoumpoulis I

However, it can also decrease stomach acid production and delay the absorption of essential nutrients, particularly vitamin B12

The primary objective was to determine whether dapagliflozin 10 mg reduces the incidence of the composite endpoint of 50% sustained decline in eGFR, progression to end-stage kidney disease (ESKD) (defined as sustained eGFR 40% and evidence of structural heart disease to determine whether dapagliflozin reduces the risk of cardiovascular death, hospitalization for heart failure or urgent heart failure visits

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