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cm , are missing at this point, likely due to experimental challenges

NCTC1469 cells, a normal mouse hepatocyte cell line, were obtained from the American Type Culture Collection and were cultured in DMEM containing 10% (v/v) fetal horse serum, 2 mM glutamine, 5 U/mL penicillin, and 50 g/mL streptomycin at 37 C in a humidified O 2 /CO 2 (19:1) atmosphere

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Additionally, oxidative stress can impair the clearance mechanisms of A, including autophagy and proteasomal degradation, contributing to its accumulation [154]