The injections specifically target the platysma muscle, which spans the lower part of the face and extends to the clavicle
The longer-term concern is oncological
However, no significant difference was observed in marble burying behavior between MIA mice and control mice demonstrating 48.9 6.3% buried and 50.2 5.8% buried, respectively
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Reinheit des erhaltenen Salzes: 99,4% (HPLC)
The results of the open-label extension showed also that longer exposure to opicapone did not increase motor complication rates and interestingly a larger percentage of patients randomised to opicapone in the double-blind phase (early starters) remained free of motor complications (score of 0 on the MDS-UPDRS part IV) compared to those starting opicapone at open-label baseline (80.2% vs 69.7%, p = 0.1)