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Because these mechanisms reinforce one another, the overall metabolic effect can appear robust even if any single component varies, which is another reason a clean, isolated read on the gastric-emptying contribution is so hard to obtain from combination-drug outcome data

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For patients without absorption disorders, high-dose oral B12 supplements (1,000-2,000 mcg daily) have been shown to be comparably effective to injections in correcting mild to moderate deficiency

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Everyones body responds differently to caffeine