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Avoid exceeding the recommended upper limits for any B vitamin without medical supervision

elevated triglycerides (defined as 150 mg/dL), decreased High Density Lipoprotein (HDL) (ranges below 40 mg/dL in men and 50 mg/dL in women), elevated blood pressure (defined as systolic blood pressure above 130 mmHg or diastolic blood pressure above 85 mmHg) and elevated fasting glucose (defined as blood glucose above 100 mg/dL)

Individuals with Gastrointestinal Conditions: Certain gastrointestinal conditions, such as celiac disease, Crohns disease, or gastrointestinal surgery, can impair nutrient absorption