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Both semaglutide and tirzepatide are GLP-1-based injectable weight loss medications, but tirzepatide is a dual GIP/GLP-1 receptor agonist, meaning it activates an additional hormonal pathway that amplifies metabolic effects

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Recently, single-cell (sc) RNA sequence (RNA-seq) analyses of immune cells from brain samples of an AD model (5XFAD) identified microglial clusters named disease-associated microglia (DAM), which appear under neurodegenerative conditions 21

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