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The Lancet 2026 For deeper curations and analysis on digital health, AI, and evidence-based decision-making, I share regular insights in my newsletter Evidence Decoded.Join here: This is becoming one of the most well-evidenced drug classes in modern medicine

Downregulation of GLP-1 and GIP receptor expression by hyperglycemia possible contribution to impaired incretin effects in diabetes

N Engl J Med 355(23):24272443

This might include adjusting the dosage or combining the medication with other treatments, depending on the patients overall health, weight loss goals, and any coexisting conditions

Use containers that feel substantial when picked up

Safety : Never share pens with others, even if the needle is changed