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Autoimmune Dis 2014:743616

Kreuter J, Shamenkov D, Petrov V, Ramge P, Cychutek K, Koch-Brandt C, et al

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The highest inflammatory challenge (1.0 mg/kg LPS) triggered rapid astrocyte activation in both hippocampus (BH-adjusted P =0.047) and whole brain (BH-adjusted P =410 -6 ), with sustained activation evident in the whole brain through the sub-chronic phase (BH-adjusted P =210 -4

We therefore undertook separate meta-analysis for the occipital and medial frontal cortex