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[6] If this happens, vitamin B 12 deficiency may result in sense loss, loss of sensation in the feet, difficulty walking, poor balance, blurred vision, changes in reflexes, muscle weakness, decreased smell and taste, decreased level of consciousness, mood changes, memory loss, depression, irritability, clumsiness, disorientation, dementia and, in severe cases, psychosis

There are also certain drugs and health conditions that can increase the likelihood of developing a B12 deficiency such as: alcohol abuse, antacid use, smoking, celiac disease, other digestive concerns, pregnancy, a strict vegetarian or vegan diet, and even natural aging

LEfSe analysis provided a secondary measure to establish differences between treatment groups in addition to the one-way ANOVA/KruskalWallis tests performed on each genus/phylum

B12 is present in a variety of food sources (mainly animal-based products), where it is bound to protein molecules

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