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Antifibrotic effects of hepatocyte growth factor on endothelial-to-mesenchymal transition via transforming growth factor-beta1 (TGF-1)/Smad and Akt/mTOR/P70S6K signaling pathways

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Lu S, Wang J, Chitsaz F, Derbyshire MK, Geer RC, Gonzales NR, et al

While overall decline rates were similar between groups, post-hoc subgroup analysis indicated slower cognitive decline in early-onset patients (aged 65 or younger) compared to placebo, as measured by the Alzheimer's Disease Assessment Scale cognitive subscale and Clinical Dementia Rating Scale [5][18]

PubMed 19