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Consistent with a decrease in oxidant stress in E-Sol5, especially at supercooled temperatures, decreased ROS-mediated conversion of the antioxidant urate into allantoate was observed throughout storage (Supplemental Fig

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To enable such assessments, the ICE Bioscience team established stable COS7 cell lines overexpressing rat, mouse, dog, and monkey CTR and AMY3R, and developed a fully optimized HTRF-cAMP assay

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