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Local application options and antibacterial activity are the main advantages reported in numerous studies for such biopolymers (Wu et al., 2022

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demonstrated this by fusing Human platelet membranes onto 100-nm PLGA cores to create PNPs [64]

doi:10.2147/copd.2006.1.4.425

Lower concentrations (100-200 g/ml) require larger injection volumes (2-5ml per dose), which may cause discomfort at the injection site and require multiple injection sites if volumes exceed 2ml