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In clinical trials of semaglutide injection for type 2 diabetes mellitus (T2DM), cholelithiasis was reported in 1.5% and 0.4% of patients-treated with semaglutide 0.5 mg and 1 mg subcutaneous injection, respectively

Studies have shown that sitagliptin is a selective and potent inhibitor (greater than 80%) of the DPP-4 enzyme

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