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Its ubiquitination and degradation can limit the activation of antioxidant genes, thereby reducing the survival and proliferation of cancer cells

Wang Z, Zhang H, Liu Z, Ma Z, An D, Xu D

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The effectiveness of once-daily subcutaneous liraglutide administration for weight loss management in adults was established in five large-scale randomized multicentre phase 3 trials [49,50,51,52,53], four of which were part of the SCALE program (Satiety and Clinical AdiposityLiraglutide Evidence in nondiabetic and diabetic individuals), leading to its approval at a dose of 3.0 mg subcutaneous once-daily (weekly increased from 0.6 mg to 3 mg/day)

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