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Nausea (43%), diarrhea (33%), and vomiting (21%) are the most common, consistent with other GLP-1 medications

[9] STEP-1 : In patients with obesity without diabetes, semaglutide resulted in ~15% mean weight loss over 68 weeks

January 2022: Novo Nordisk announced the launch of oral semaglutide in India for the treatment of type 2 diabetes

Some researchers lose 3 to 5% of body weight during the first 12 weeks of escalation, while others see minimal change until reaching 8mg or higher

Introduction The development of new compounds in recent decades has substantially improved the pharmacotherapy of type 2 diabetes (T2D) by improving achievement of metabolic targets while mitigating specific side effects (e.g., weight gain, hypoglycemia) frequently observed in patients treated with traditional hypoglycemic drugs such as insulin and sulfonylureas

2023, doi: 10.1056/NEJMoa2307563