doi: 10.3389/fphar.2014.00179 Received 25 April 2014 Accepted 14 July 2014 Published 31 July 2014 Volume 5 - 2014 Edited by Alfonso Pompella, Universit di Pisa, Italy Reviewed by Jiang Liu, University of Southern California, USA
Healthy Aging: Glutathione status is associated with aging
This is supported by some of the existing research on the compound
The active form, 1,25(OH) 2 D 3 , is known for its neuroprotective effects in conditions like multiple sclerosis (MS), Alzheimers disease, and other disorders [141]
Collectively, these design principles establish a biointelligent framework for HAGSH scaffold development, where structural adaptability, biochemical responsiveness, and polymer network precision converge to create mechanically robust yet biologically dynamic systems ideally suited for redox-regulated wound repair
Although preclinical studies have illustrated that pure nanotherapeutics possess some therapeutic functions, challenges still remain in their low accumulation at the targeted areas and easy leakage, which may cause therapeutic inefficiency to hinder subsequent clinical translation 23,24,25
