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CagriSema clinical trial results The REDEFINE 1 trial enrolled adults with obesity or overweight (BMI of 30 or greater, or 27 or greater with at least one weight-related comorbidity) without type 2 diabetes

Isoprenaline control rats exhibited hemorrhagic gastric lesions (5.5 1.0, means SD, mm, sum of the longest lesions diameters), while BPC 157-treated rats had spared gastric mucosa ( p 0.05, vs

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28,46 Further preclinical experiments showed that the combined activation of both GLP-1 and GIP receptor agonists had superior glucose-lowering efficacy compared to activation of either receptor alone

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