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Most gastrointestinal adverse events occurred during or shortly after the dose escalation phase, suggesting that the initial adjustment period is critical for managing these effects

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Hydration is equally important, particularly if you are experiencing gastrointestinal side effects such as nausea, vomiting, or diarrhea

LPO products can abrogate the function of PI3K specifically by caused conformational change that leads to the removal of the catalytic subunit or by competition with the regulatory subunit [111,112,113]