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This study was designed to systematically investigate the cartilage-protective effects of AOD9604, both alone and in combination with HA, using a well-established collagenase-induced OA rabbit model

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Experimental models have examined its influence on vascular endothelial growth factor receptor-2 (VEGFR2) signaling, including activation of downstream VEGFR2AkteNOS pathways associated with endothelial cell proliferation and vascular signaling processes

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