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In HFD-induced rat models of insulin resistance and hepatic steatosis, FBA showed comparable therapeutic efficacy to NaBu, with significantly greater potency in reducing pro-inflammatory parameters, lipid accumulation, and HMGB1 transcription [103]

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In presence of oxidant agents the NADPH production through the HMP is stimulated multiple times so that the NADPH and GSH levels maintain stable

These include Iodine deficiency