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Yes, you can pause or discontinue semaglutide at any timeit carries no withdrawal risk because it's not habit-forming

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2) insulin resistance leading to decreased glucose uptake by peripheral tissues (i.e., muscle and adipose)

adults reported using GLP-1 medications for weight loss, more than double the percentage reported in early 2024

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If youve tracked food, increased activity, and tried multiple approaches over months or years, and the weight either will not move or keeps coming back, that pattern often points to underlying physiological resistance that diet alone cannot overcome