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Common side effects include: Injection site reactions pain, redness, or swelling at the injection site Mild diarrhoea or gastrointestinal upset usually transient Skin reactions itching or rash (uncommon) Hypokalaemia rare, occurring when severe megaloblastic anaemia is corrected rapidly Serious adverse effects are extremely rare but may include anaphylaxis in hypersensitive individuals

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For patients pairing B12 with NAD+ IV therapy during energy-focused protocols, B12 typically runs weekly between NAD+ sessions and helps sustain the cellular energy benefits between infusions

Production of acetylcholine, which is one of the major neurotransmitters in the body

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